Sex Hormone Binding Globulin (SHBG)
What It Is
SHBG is a protein that binds to sex hormones, regulating their availability in the body.
Why It Matters
SHBG levels affect how much free testosterone and oestrogen is available. It is important for interpreting hormonal results.
If Levels Are High
Elevated SHBG reduces free testosterone levels and can occur with liver disease, hyperthyroidism, or ageing.
If Levels Are Low
Low SHBG increases free testosterone and may be seen in obesity, PCOS, or hypothyroidism.
Preparation
Morning sample recommended.
How Often to Test
As clinically indicated alongside testosterone testing.
Important Disclaimer
This information is for educational purposes only and does not constitute medical advice or diagnosis. Results should be interpreted in clinical context by a qualified healthcare professional. If you have severe symptoms or urgent concerns, seek urgent medical help.